KnowraSecond-generation antihistamineLinked fromLinked fromThe 8 pages that link to Second-generation antihistamine, each with the reason it gives.All 8Broader topic 2Related 1Narrower topic 1Compared with 4Histamine H1 receptorCompared with: These drugs target peripheral H1 effects with less influence on wakefulness.HydroxyzineCompared with: This newer group is typically less sedating than hydroxyzine.PromethazineCompared with: This drug class contrasts with promethazine's brain-penetrating, often drowsy-making profile.CyclizineCompared with: These drugs usually treat allergies rather than motion sickness because they have less central action.