Linked from

The 31 pages that link to Autophagy, each with the reason it gives.

• ApoptosisCompared with: Autophagy recycles cellular components and is not itself synonymous with apoptotic cell death.

• PhagocytosisCompared with: Autophagy degrades material originating inside the cell, unlike phagocytosis.

• AgingRelated: Declining autophagic activity can allow cellular waste to build up during aging.

• LysosomeNarrower topic: Lysosomes complete the degradation step in major forms of autophagy.

• FastingRelated: Nutrient scarcity can influence autophagy, though effects in humans vary and remain under study.

• EndocytosisCompared with: Unlike endocytosis, it begins by enclosing material from inside the cell rather than the extracellular space.

• OrganelleRelated: Autophagy removes damaged organelles and recovers their molecular building blocks.

• CytoplasmRelated: It clears or recycles cytoplasmic material, including damaged organelles.

• Crohn's diseaseRelated: Impaired autophagy can weaken intestinal handling of microbes in people with Crohn's disease.

• AMP-activated protein kinaseRelated: AMPK can promote autophagy when energy is scarce and cellular resources must be recycled.

• ProteolysisRelated: Autophagy routes proteins and other cellular material to proteolytic enzymes.

• Lysosomal storage diseaseRelated: Lysosomal dysfunction can impair the final breakdown step of autophagy.

• VacuoleRelated: In fungi and plants, vacuoles receive material targeted for cellular recycling.

• Ubiquitin–proteasome systemCompared with: Unlike the proteasome, autophagy can engulf large structures and aggregates.

• Calorie restrictionRelated: Nutrient scarcity can promote cellular recycling, one proposed route to health effects.

• Intermittent fastingRelated: Fasting is studied as a possible influence on autophagy, though effects in humans remain uncertain.

• LongevityRelated: Its role in cellular cleanup connects maintenance to lifespan.

• Programmed cell deathRelated: Autophagy often supports survival, but its machinery can contribute to cell death in some contexts.

• UbiquitinRelated: Ubiquitin marks can help identify cargo for selective autophagy.

• Muscle atrophyRelated: Excessive or altered autophagy can contribute to muscle wasting.

• Endomembrane systemRelated: It connects internal recycling to the system’s lysosomal machinery.

• Christian de DuveRelated: Lysosome research helped establish the organelle’s central role in cellular self-digestion.

• SirolimusRelated: mTORC1 inhibition can release a brake on autophagy, linking sirolimus to cellular recycling.

• ChloroquineRelated: Chloroquine can block late autophagy by impairing the breakdown of material in lysosomes.

• PhagocyteCompared with: Autophagy digests intracellular material; phagocytosis brings material in from outside.

• ProteasomeCompared with: Unlike the proteasome’s selective protein breakdown, autophagy can degrade larger structures and organelles.

• Schizosaccharomyces pombeRelated: Fission yeast enables genetic analysis of conserved autophagy machinery.

• Yoshinori OhsumiNarrower topic: It is the process whose machinery and genetic control Ohsumi investigated.

• Biomolecular & subcellular processesRelated: It clears damaged components and reallocates their molecular building blocks.

• Glycogen storage disease type IIRelated: Impaired lysosomal clearance disrupts autophagic material handling in affected muscle.

• Sanfilippo syndromeRelated: Lysosomal dysfunction can disrupt cellular recycling pathways, including autophagy.