KnowraCisplatinLinked fromLinked fromThe 21 pages that link to Cisplatin, each with the reason it gives.All 21Broader topic 13Related 6Compared with 2Coordination complexBroader topic: This coordination complex damages cancer-cell DNA after ligand substitution.LigandBroader topic: Its chloride ligands are replaced in aqueous environments, enabling platinum to bind DNA.Coordination chemistryBroader topic: Its square-planar platinum center binds cellular targets after ligand substitution.NephrotoxicityBroader topic: Its tubular toxicity is a major limit on treatment dosing.OtotoxicityBroader topic: Cisplatin can cause lasting, often high-frequency hearing loss.Chemotherapy-induced peripheral neuropathyBroader topic: Cisplatin neuropathy often emerges with cumulative exposure and may persist after treatment.Square planar molecular geometryBroader topic: Its geometry fixes the relative positions of the ligands involved in DNA binding.Testicular cancerBroader topic: It is the key drug behind the high curability of metastatic testicular cancer.Group 10 elementBroader topic: This platinum compound shows how a group 10 metal can become a medicine.Inorganic compoundBroader topic: It demonstrates how an inorganic metal complex can act as a medicine.Coordination sphereBroader topic: Its ligand sphere governs aquation and DNA binding in cancer treatment.History of cancerBroader topic: Its success in testicular cancer helped demonstrate that chemotherapy could cure some advanced cancers.Inorganic chemicalsBroader topic: It demonstrates how an inorganic complex can act as a medicine.