Linked from

The 33 pages that link to Citric acid cycle, each with the reason it gives.

• Cellular respirationBroader topic: It extracts additional electrons from carbon fuel for delivery to the respiratory chain.

• Citric acidRelated: Citric acid is a central intermediate in this metabolic pathway, though it is not its only role.

• Nicotinamide adenine dinucleotideRelated: Several cycle reactions reduce NAD⁺ to NADH as carbon is oxidized.

• Acetyl-CoARelated: It accepts acetyl-CoA to begin oxidation of the acetyl group.

• GluconeogenesisRelated: Its intermediates can supply carbon for gluconeogenesis, though the cycle itself oxidizes fuel.

• BiochemistryBroader topic: It connects the breakdown of fuels to cellular energy transfer.

• DecarboxylationNarrower topic: Two of its reactions release carbon dioxide through oxidative decarboxylation.

• Aerobic respirationRelated: It generates most of the NADH and FADH₂ that feed the respiratory chain.

• Coenzyme ARelated: Acetyl-CoA supplies the acetyl group that enters the cycle.

• Adenosine diphosphateRelated: Its substrate-level phosphorylation can convert ADP to ATP in some tissues.

• KetogenesisCompared with: When its capacity to use acetyl-CoA is constrained, more acetyl-CoA can enter ketogenesis.

• NADHRelated: Several of its reactions produce NADH for mitochondrial respiration.

• Substrate-level phosphorylationNarrower topic: One cycle reaction forms GTP or ATP by substrate-level phosphorylation.

• CitrateCompared with: The pathway name and citrate are related, but one is a process and the other a molecule.

• Albert Szent-GyörgyiRelated: His work on fumaric acid anticipated later understanding of cyclic pathways in cellular oxidation.

• Malic acidRelated: Malate is oxidized to oxaloacetate in the cycle's final reaction.

• Acetic acid fermentationRelated: It can support further oxidation of acetate after ethanol-derived acetic acid accumulates.

• CoenzymeRelated: NAD⁺, FAD, and coenzyme A participate in its linked reactions.

• Lemon juiceCompared with: Despite the shared name, this cellular pathway is not the source of lemon juice’s citric acid.

• Pyruvate dehydrogenase complexNarrower topic: It receives the acetyl group produced by the complex.

• Succinic acidNarrower topic: Succinic acid is an intermediate in this cycle, where it is usually present as succinate.

• Succinate dehydrogenaseNarrower topic: Succinate dehydrogenase catalyzes one of the cycle’s eight central reactions.

• Fumaric acidNarrower topic: Fumarate is one of the cycle’s four-carbon intermediates.

• Methylmalonic acidRelated: The pathway connects methylmalonic acid metabolism to cellular energy production through succinyl-CoA.

• Pyruvate carboxylaseNarrower topic: The enzyme restores oxaloacetate and other intermediates withdrawn from this cycle.

• Succinyl-CoANarrower topic: Succinyl-CoA is one of the cycle's intermediates, linking oxidation to biosynthesis.

• Hans KrebsBroader topic: Krebs’s best-known discovery maps this cycle’s sequence of reactions.

• Pantothenic acidRelated: Pantothenic acid enters the cycle in acetyl-CoA, a key carbon input.

• CatabolismBroader topic: It oxidizes products of carbohydrate, fat, and protein breakdown.

• Alpha-ketoglutaric acidNarrower topic: Alpha-ketoglutarate is produced from isocitrate and converted to succinyl-CoA within this cycle.

• Oxaloacetic acidNarrower topic: Oxaloacetate condenses with acetyl-CoA and is regenerated as the cycle proceeds.

• Pyruvic acidRelated: Pyruvate supplies acetyl-CoA to the cycle after oxidative decarboxylation.

• MitochondriaRelated: It supplies NADH and FADH₂ to the mitochondrial electron transport chain.