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The 19 pages that link to Proton pump inhibitor, each with the reason it gives.

• Gastroesophageal reflux diseaseRelated: These drugs reduce the acidity of refluxate and are a common treatment.

• Gastric acidRelated: These drugs treat acid-related disease by blocking the final step of secretion.

• Peptic ulcer diseaseRelated: Acid suppression promotes ulcer healing and is commonly combined with antibiotics for H. pylori.

• Gastrointestinal bleedingRelated: It is used in selected upper-tract bleeds, especially those caused by peptic ulcers.

• AntacidCompared with: Unlike antacids, these medicines reduce acid production and generally take longer to provide full relief.

• Helicobacter pyloriRelated: Acid suppression supports ulcer healing and improves the effectiveness of eradication therapy.

• HypomagnesemiaRelated: Long-term use has been associated with impaired magnesium absorption and deficiency.

• Parietal cellRelated: These drugs target the proton pump that parietal cells use to secrete acid.

• Zollinger–Ellison syndromeRelated: High-dose acid suppression controls symptoms and prevents complications while tumors are evaluated.

• Enteric coatingBroader topic: Many proton-pump inhibitors need protection from stomach acid before intestinal absorption.

• FamotidineCompared with: This drug class generally produces stronger, longer-lasting acid suppression than famotidine.

• Helicobacter pylori eradicationRelated: Acid suppression supports antibiotic activity and is a standard part of many eradication regimens.

• CimetidineCompared with: Unlike cimetidine, it blocks the final acid-secretion step rather than histamine signaling.

• James BlackCompared with: This later drug class supplanted H2 blockers in many treatments for acid-related disease.

• Eosinophilic esophagitisRelated: Proton pump inhibitors can induce remission in some people with eosinophilic esophagitis.

• Barry MarshallCompared with: They support ulcer healing, but Marshall’s discovery showed why acid suppression alone may not cure infection-driven disease.

• LansoprazoleNarrower topic: Lansoprazole belongs to this drug class and shares its acid-suppressing mechanism.

• PantoprazoleNarrower topic: Pantoprazole belongs to this drug class and shares its acid-suppressing mechanism.

• RanitidineCompared with: These drugs generally suppress acid more strongly and became preferred for many conditions.