Linked from

The 29 pages that link to Smallpox, each with the reason it gives.

• Columbian ExchangeBroader topic: Its arrival in the Americas contributed to catastrophic population loss among Indigenous peoples.

• Hernán CortésRelated: The epidemic of 1520 devastated Indigenous communities during the struggle for Tenochtitlan.

• Herd immunityBroader topic: Its eradication demonstrates how vaccination can interrupt transmission across populations.

• TenochtitlanRelated: An epidemic weakened Tenochtitlan during the conflict and siege.

• MeaslesCompared with: Both diseases caused fever and rash, but smallpox lesions and progression differed markedly.

• AnthraxCompared with: It is a viral threat often compared with anthrax in biological preparedness.

• Siege of TenochtitlanRelated: An epidemic during the preceding 1520 crisis weakened Tenochtitlan before the final siege.

• Smallpox vaccineRelated: Preventing this disease was the vaccine’s defining purpose.

• European exploration of the PacificRelated: Introduced epidemics devastated some Pacific communities after sustained outside contact.

• Smallpox eradicationNarrower topic: The disease’s human-only reservoir and visible symptoms helped make its transmission traceable and interruptible.

• Varicella-zoster virusCompared with: Its rash disease could resemble chickenpox, but variola virus was unrelated and far more lethal.

• La Noche TristeRelated: The epidemic weakened Tenochtitlan during the conflict that followed the retreat.

• Third plague pandemicCompared with: Smallpox was another feared epidemic disease, but it spread person to person rather than through plague-bearing fleas.

• Antonine PlagueCompared with: It is the leading proposed cause, though surviving descriptions cannot establish the diagnosis.

• Fall of TenochtitlanRelated: The epidemic weakened Tenochtitlan’s population during the conquest.

• Lady Mary Wortley MontaguRelated: The disease’s severe mortality explains the urgency of Montagu’s inoculation campaign.

• VariolationRelated: Variolation used material from this disease to induce a controlled infection.

• Historical epidemiologyRelated: Its changing burden can be traced through records of outbreaks, inoculation, and vaccination.

• Spanish conquest of the MayaRelated: Epidemics weakened Maya communities during the period of Spanish expansion.

• Thomas SydenhamBroader topic: His writings on smallpox show how he compared diseases by their observable course.

• Huayna CapacRelated: Accounts associate the epidemic that killed Huayna Capac with the disease’s spread ahead of Spanish forces.

• Dzungar genocideRelated: Smallpox epidemics compounded deaths among Dzungars during Qing military operations.

• ChickenpoxCompared with: Smallpox also caused a blistering rash, but its lesions and distribution differed from chickenpox.

• AztecsRelated: The epidemic weakened Tenochtitlan during the struggle for the city.

• Ueda AkinariRelated: Akinari survived smallpox in childhood, which damaged his fingers and influenced his life story.

• Abu Bakr al-RaziRelated: Al-Razi’s account distinguished its symptoms from those of measles.

• Turlough O'CarolanRelated: Accounts of O'Carolan's biography say smallpox caused his blindness.

• Voyages of Christopher ColumbusRelated: Diseases introduced through sustained contact devastated Indigenous populations in the Americas.

• Wyandot peopleRelated: Epidemics, including smallpox, severely reduced Indigenous populations during the colonial period.